Reports to: Head of R&D

Location: San Francisco, CA

About the Company
Delve Bio is on a mission to improve patient outcomes and lower healthcare costs by bringing cutting-edge genomic technology to infectious diseases. We are a well-funded biotech company backed by some of the most experienced operators and investors in the industry. Our co-founders are highly experienced researchers, clinicians, and entrepreneurs, including Dr. Matthew Meyerson, MD. PhD (Director of Cancer Genomics at Broad Institute and co-founder of Foundation Medicine) and Dr. Joseph DeRisi, PhD (Professor at the University of California San Francisco and President of the Chan Zuckerberg Biohub). Delve Bio launched its flagship metagenomic next generation sequencing platform Delve Detect in 2024, providing game-changing, infectious disease testing to patients across the US.

About the Role

This is an opportunity to contribute to assay development in a small R&D team within a Series A diagnostics startup. The Delve R&D team works to improve the performance and sensitivity of Delve’s LDT (Laboratory Developed Test), which is run in a clinical laboratory separate from the R&D department. Most of the Delve team is remote, but this opportunity is an in-person lab-based role in a startup incubator in San Francisco. This is a temporary hourly contractor role beginning in June 2025.

You will work closely with R&D scientists to move product development forward and improve Delve’s methods. Examples of work may include evaluating new additions to the methodology, developing a plan for testing their impact on Delve’s LDT, executing experiments to incorporate them, and evaluating the resulting data.

Responsibilities

• Maintaining and operating automated liquid handling instrumentation such as an Agilent Bravo instrument
• Nucleic acid extraction and sequencing library preparation
• Nucleic acid quantification and quality control
• Illumina sequencing
• Maintaining experiment documentation in Delve’s ELN (Electronic Laboratory Notebook)
• Basic Next Generation Sequencing (NGS) data analysis
• Attend meetings with team members across all departments
• Work closely with the Bioinformatics team
• Present your work progress to leadership
• Contribute to laboratory management and operations

Requirement 

• Bachelor’s or master’s degree in a scientific field and 2+ years of experience in a biotech or pharma environment
• Experience with automated liquid handling (Agilent Bravo preferred)
• Experience with Illumina-based methodology for both DNA and RNA sequencing
• Strong written and verbal communication skills and experience recording results in an electronic lab notebook (ELN)
• Proven track record of independent experimental design, execution and data analysis in an assay development context
• Ability to work closely cross-functionally, including with other employees who are virtual
• A desire and enthusiasm to help patients and solve scientific problems
• The following are preferred but not required:
  • Experience working under Design Controls
  • Familiarity with LDT development and validation in a CLIA setting, or IVD development of FDA-regulated IVD
  • Familiarity with microbiology, virology or other infectious disease-related areas
  • Experience with bioinformatics (e.g. Python or R coding)
  • Experience using Tableau for data visualization

Equal Employment Opportunity
Delve provides equal employment opportunities to all employees and applicants for employment without regard to race, color, national origin, religion, sexual orientation, gender, gender identity or expression, age, veteran status, disability, pregnancy or conditions related to pregnancy, or genetics.

To apply, submit resume to careers@delve.bio.